Paraneoplastic chorea with leukoencephalopathy presenting with obsessive–compulsive and behavioral disorder
Identifieur interne : 003806 ( Main/Exploration ); précédent : 003805; suivant : 003807Paraneoplastic chorea with leukoencephalopathy presenting with obsessive–compulsive and behavioral disorder
Auteurs : Susanne Muehlschlegel [États-Unis] ; Michael S. Okun [États-Unis] ; Kelly D. Foote [États-Unis] ; Dominique Coco [États-Unis] ; Anthony T. Yachnis [États-Unis] ; Hubert H. Fernandez [États-Unis]Source :
- Movement Disorders [ 0885-3185 ] ; 2005-11.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
- Aged, Autopsy (methods), CV2 paraneoplastic antibodies, Caudate Nucleus (pathology), Chorea, Chorea (complications), Chorea (pathology), Dementia, Vascular (pathology), Dementia, Vascular (physiopathology), Female, Humans, Leucoencephalopathy, Magnetic Resonance Imaging (methods), Nervous system diseases, Obsessive compulsive disorder, Obsessive-Compulsive Disorder (complications), Obsessive-Compulsive Disorder (pathology), Paraneoplastic syndrome, leukoencephalopathy, obsessive–compulsive disorder, paraneoplastic chorea.
- MESH :
- complications : Chorea, Obsessive-Compulsive Disorder.
- methods : Autopsy, Magnetic Resonance Imaging.
- pathology : Caudate Nucleus, Chorea, Dementia, Vascular, Obsessive-Compulsive Disorder.
- physiopathology : Dementia, Vascular.
- Aged, Female, Humans.
Abstract
Chorea is a rare manifestation of paraneoplastic disease and is associated with CV2/CRMP‐5 antibodies. Obsessive–compulsive disorder and large‐scale white matter abnormalities on MRI have not been previously reported in association with these antibodies. We report on a case of CV2 paraneoplastic syndrome with obsessive–compulsive behavior preceding the motor manifestations of chorea with associated leukoencephalopathy on MRI. The literature on paraneoplastic chorea is reviewed. © 2005 Movement Disorder Society
Url:
DOI: 10.1002/mds.20570
Affiliations:
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Le document en format XML
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<term>Chorea (complications)</term>
<term>Chorea (pathology)</term>
<term>Dementia, Vascular (pathology)</term>
<term>Dementia, Vascular (physiopathology)</term>
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<term>Leucoencephalopathy</term>
<term>Magnetic Resonance Imaging (methods)</term>
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<term>obsessive–compulsive disorder</term>
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<front><div type="abstract" xml:lang="en">Chorea is a rare manifestation of paraneoplastic disease and is associated with CV2/CRMP‐5 antibodies. Obsessive–compulsive disorder and large‐scale white matter abnormalities on MRI have not been previously reported in association with these antibodies. We report on a case of CV2 paraneoplastic syndrome with obsessive–compulsive behavior preceding the motor manifestations of chorea with associated leukoencephalopathy on MRI. The literature on paraneoplastic chorea is reviewed. © 2005 Movement Disorder Society</div>
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